11th International Workshop HBV CURE ANRS MIE
Program - July 3rd 2024
Lyon, France

8H15 - Welcome coffee
(Château de Montchat)

Welcome and Introduction

Fabien Zoulim 

Functional cure, clinical aspects

Chairs: Vincent Leroy, Fabrice Carrat

The new treatment guidelines for CHB and CHD: are we moving towards functional cure?
Markus Cornberg, Hanover

Impact of HBV DNA integration on functional cure
Patrick Kennedy, London

Roundtable discussion

Mechanisms of viral persistence

Chairs: David Durantel, Hélène Strick-Marchand

Integrative analysis of HBV and immune cells in the liver compartment during antiviral therapy
Michael Biermer, Janssen Belgium

Novel insight in the regulation of cccDNA transcription
Barbara Testoni, Lyon

Mechanism of exhaustion of B and T cells and path for functional revovery
Robert Thimme, Freiburg

Roundtable discussion

11H00 - Coffee break
(Château de Montchat)

Flash communications / Young investigators

Chairs: Christine Neuveut, Patrick Soussan

Young investigators,

Role of H2A.Z histone variants on HBV replication
Basile Jay, Montpellier

Understanding the initial phase of HBV assembly: L-induced recruitment of empty and full capsids in late-endocytic-related domains
Carla Vanessa Sarabia Vega, Tours

Development of FXR agonists as antivirals against hepatitis viruses
Romain Barnault, Lyon

Capsid assembly modulators against HBV: old molecules with new mechanisms of action
Valerio Taverniti, Strasbourg

Base Editing to inhibit HBsAg expression
Anuj Kumar, Lyon

Patient perspectives on HBV cure

Selly Sickout (SOS Hépatites) & Milan Mishkovikj (ELPA)

12H50 - Lunch break
(Château de Montchat)

HDV session

Chairs: Julie Lucifora, Vincent Thibault

HDV origin in Homo Sapiens
Frederic Le Gal, Bobigny

Intrahepatic decay of HDV during Bulevirtide therapy
Miroslava Subic Levrero, Lyon

Insight on HDV – host cell interactions for drug discovery
Eloi Verrier, Strasbourg

Mode of action of Nucleic Acid Polymers in HDV infection
Massimo Levrero, Lyon

Roundtable discussion

15H20 - Coffee break
(Château de Montchat)

Drug development

Chairs: Linda Wittkop, Fabien Zoulim

Results of clinical trials of novel cure strategies
Marc Bourlière, Marseille

CAM inhibitors as backbone treatments for functional cure
Raymond Schinazi, Atlanta

Targeting HBV RNAs with novel ASOs
Guofeng Cheng, AusperBio

Immunological correlates of functional cure
Georg Lauer, Boston

DC-targeting vaccines for HIV and emerging infectious diseases: perspectives for HBV
Yves Levy, Créteil

Roundtable discussion: HBV & HDV cure challenges

Conclusions and Farewell

Chairs: Fabien Zoulim